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Using Historical Data With Bayesian Methods in Early Clinical Trial Monitoring

โœ Scribed by French, Jonathan L.; Thomas, Neal; Wang, Cunshan

Book ID
118133789
Publisher
Informa UK (American Statistical Association)
Year
2012
Tongue
English
Weight
233 KB
Volume
4
Category
Article
ISSN
1946-6315

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โœ PETER M. FAYERS; DEBORAH ASHBY; MAHESH K. B. PARMAR ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 293 KB ๐Ÿ‘ 2 views

Many clinical trials organizations use regular interim analyses to monitor the accruing results in large clinical trials. In disease areas such as cancer, where survival is usually a major outcome variable, ethical considerations may lead to a stipulated requirement for data monitoring of mortality.