Using Alzheimer's disease as a model for genetic risk disclosure: implications for personal genomics
β Scribed by JS Roberts; KD Christensen; RC Green
- Book ID
- 110889297
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 587 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0009-9163
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We performed a community-based study to investigate the relationship of genetic susceptibility and head injury to Alzheimer's disease (AD) in 138 patients with AD and 193 healthy elderly control subjects. Data concerning presence or absence of dementia and certain exposures were also obtained from 7
## Abstract Alzheimer's disease (AD) differs from other forms of dementia in its relation to amyloid Ξ² peptide (AΞ²). AΞ², a proteolytic product of amyloid precursor proteins (APP), has a toxic effect on neuronal cells, which involves perturbation of their Ca^2+^ homeostasis. This effect implies that