✦ LIBER ✦

Usefulness of the calculated apparent diffusion coefficient value in the differential diagnosis of retroperitoneal masses

✍ Scribed by Tomohiro Nakayama; Kengo Yoshimitsu; Hiroyuki Irie; Hitoshi Aibe; Tsuyoshi Tajima; Kenji Shinozaki; Akihiro Nishie; Yoshiki Asayama; Daisuke Kakihara; Shuji Matsuura; Hiroshi Honda

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 952 KB
Volume: 20
Category: Article
ISSN: 1053-1807
DOI: 10.1002/jmri.20149

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Purpose

To elucidate whether or not the apparent diffusion coefficient (ADC) values calculated from echo‐planar diffusion‐weighted (EPDW) MR images are useful in the differential diagnosis of retroperitoneal masses.

Materials and Methods

In 50 patients with known retroperitoneal masses, EPDW images were performed with b‐factors of 0–1100 seconds/mm^2^. The final histologic diagnoses of these lesions were as follows: 12 malignant lymphomas, four other malignant mesenchymal neoplasms, 25 malignant epithelial neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions. The ADC values obtained for the solid portion of the lesions were used to represent each lesion, and the values of the histologic groups were compared.

Results

The respective value of ADC for 12 malignant lymphomas, four other mesenchymal neoplasms, seven benign mesenchymal neoplasms, and two nonneoplastic lesions were as follows: 0.66 ± 0.26, 1.26 ± 0.50, 0.90 ± 0.20, 1.87 ± 0.48, 1.32 ± 0.20 × 10^−3^ mm^2^/second. The ADC value of the malignant lymphoma was significantly lower than that of the other malignant mesenchymal lesions, and was also lower than the ADC of the benign lesions. The ADC value of the malignant epithelial neoplasms was lower than that of the benign mesenchymal tumors. The ADC values of the malignant and benign lesions were 0.94 ± 0.30 and 1.75 ± 0.49 × 10^−3^ mm^2^/second, respectively, which also demonstrated a significant difference.

Conclusion

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