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Usefulness of plasma epigenetic changes of five major genes involved in the pathogenesis of colorectal cancer

✍ Scribed by Pack, Seung-Chul; Kim, Hye-Ran; Lim, Sang-Woo; Kim, Hwan-Young; Ko, Jung-Yun; Lee, Ki-Sang; Hwang, David; Park, Seong-Il; Kang, Hoon; Park, Sang-Wook; Hong, Gun-Young; Hwang, Se-Min; Shin, Myung-Geun; Lee, Soong

Book ID
120066444
Publisher
Springer
Year
2012
Tongue
English
Weight
407 KB
Volume
28
Category
Article
ISSN
0179-1958

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Patterns of allele loss (loss of heterozygosity, LOH) have been studied in order to investigate the genetic pathways involved in the pathogenesis of three types of colorectal cancer (CRC): sporadic CRC without replication errors (RER ) (32 cases); sporadic RER+ CRC (23 cases); and ulcerative colitis