BACKGROUND. Biochemical markers of bone disease have been of interest as part of the investigation of prostate carcinoma and the monitoring of skeletal involvement. Bone isoenzyme of the alkaline phosphatase (BAP) is an indicator of the metabolism of the osteoblasts. An immunoradioanalyses with two
Usefulness of bone marrow serum acid phosphatase in staging carcinoma of the prostate
โ Scribed by Dr. Lt. Col. Ralph D. Reynolds; Maj. Bernard R. Greenberg; Col. Neil D. Martin; Col. Richard N. Lucas; Maj. Clyde N. Gaffney; Linda Hawn
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 323 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0008-543X
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๐ SIMILAR VOLUMES
In patients with nonprostatic cancer serum acid phosphatase activity is usually elevated when bone metastasis is present but not when bone metastasis is absent. The fraction responsible for serum enzyme elevation is a normal component of serum; it appears in gel electrophoresis as band 5; and is tar
Veterans (n = 771, 54-76 years of age) from the Second World War, who attended a rehabilitation program arranged by the state between the years 1979 and 1983, were screened for prostatic cancer by rectal examination of the prostate and by measurement of serum prostate-specific acid phosphatase (PAP)
Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patient