Use ofIn VivoAnimal Models to Assess Pharmacokinetic Drug-Drug Interactions
β Scribed by Cuyue Tang; Thomayant Prueksaritanont
- Book ID
- 106493980
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 304 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0724-8741
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Background: Rivaroxaban is an oral Factor Xa inhibitor. The primary objective of this communication was to quantitatively predict changes in rivaroxaban exposure when individuals with varying degrees of renal impairment are co-administered with another drug that is both a P-gp and a moderate CYP3A4