✦ LIBER ✦

Use of X-ray Co-crystal Structures and Molecular Modeling To Design Potent and Selective Non-peptide Inhibitors of Cathepsin K

✍ Scribed by DesJarlais, Renee L.; Yamashita, Dennis S.; Oh, Hye-Ja; Uzinskas, Irene N.; Erhard, Karl F.; Allen, Andrew C.; Haltiwanger, R. Curtis; Zhao, Baoguang; Smith, Ward W.; Abdel-Meguid, Sherin S.; D'Alessio, Karla; Janson, Cheryl A.; McQueney, Michael S.; Tomaszek, Thaddeus A.; Levy, Mark A.; Veber, Daniel F.

Book ID: 127228729
Publisher: American Chemical Society
Year: 1998
Tongue: English
Weight: 71 KB
Volume: 120
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja981171v

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design, Synthesis, SAR, and Molecular Mo

Design, Synthesis, SAR, and Molecular Modeling Studies of Acylthiocarbamates: A Novel Series of Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Structurally Related to Phenethylthiazolylthiourea Derivatives

✍ Ranise, Angelo; Spallarossa, Andrea; Schenone, Silvia; Bruno, Olga; Bondavalli, 📂 Article 📅 2003 🏛 American Chemical Society 🌐 English ⚖ 227 KB

Study of binary and ternary metal comple

Study of binary and ternary metal complexes containing the sulfato ligand: molecular models for selected non-catalytic sites in sulfurylaseElectronic supplementary information (ESI) available: Full listings of atomic coordinates from X-ray diffraction experiments and from molecular modelling calculations, atomic thermal displacements, bond lengths and bond angles, and computed heat of formation and heat of reaction for selected molecules and reactions, Figure relevant to selected computed structures, and Figure relevant to vibrational modes. See http://www.rsc.org/suppdata/dt/b3/b302779a/

✍ Tamasi, Gabriella; Cini, Renzo 📂 Article 📅 2003 🏛 Royal Society of Chemistry 🌐 English ⚖ 337 KB