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Use of whole-embryo culture in the study of teratogenic anti-yolk sac antibody

✍ Scribed by Freeman, S.J.; Brown, N.A.

Book ID
123277062
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
78 KB
Volume
24
Category
Article
ISSN
0278-6915

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Primary cultures of visceral yolk-sac (VYS) endodermal cells were used to assess the effects of teratogenic and nonteratogenic antibodies. When assessed by cytotoxicity assay, teratogenic antibodies appeared to be lethal to the cultured cells at high concentrations (1.25-5 mg of antibodies per ml of