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Use of transcutaneous nerve stimulation in the attacks of acute intermittent porphyria

✍ Scribed by Birger Kaada; Inge Romslo


Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
719 KB
Volume
17
Category
Article
ISSN
0020-711X

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Acute intermittent porphyria (AIP) is an autosomal dominant inborn error of metabolism that results from the half-normal activity of the third enzyme in the heme biosynthetic pathway, hydroxymethylbilane synthase (HMB-synthase). AIP is an ecogenetic condition, with 1ife.threatening acute attacks pre

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Acute intermittent porphyria (AIP) is an autosomal disorder caused by molecular abnormalities in the hydroxymethylbilane synthase (HMBS) gene coding for the third enzyme in the heme biosynthetic pathway. So far, more than 160 different mutations responsible for AIP have been identified in this gene.