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Use of the selective serotonin reuptake inhibitor citalopram in a possible animal analogue of obsessive-compulsive disorder

✍ Scribed by Dan J. Stein; Ivan Mendelsohn; Felix Potocnik; Jeanine Van Kradenberg; Charmaine Wessels

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 180 KB
Volume: 8
Category: Article
ISSN: 1091-4269
DOI: 10.1002/(sici)1520-6394(1998)8:1<39::aid-da8>3.0.co;2-0

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✦ Synopsis

Canine acral lick dermatitis (ALD) has been suggested as an animal analogue of obsessive-compulsive disorder (OCD). A series of dogs with ALD or similar conditions were treated with citalopram, the most selective of the selective serotonin reuptake inhibitors. Six of nine (66.7%) dogs showed significant improvement. Given the apparent efficacy of citalopram in the treatment of OCD and related disorders, these data provide further evidence that ALD is a useful animal analogue of OCD.

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