Use of the haldane equation for steady-state substrate inhibition in biodegradation kinetics
✍ Scribed by P. Beltrame; P. L. Beltrame; P. Carniti
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 191 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0006-3592
No coin nor oath required. For personal study only.
✦ Synopsis
Substrate inhibition in biodegradation processes typically leads to a maximum in the plot of specific degradation rate U [ = (CSo -C,)/C,O] versus substrate concentration C,. The Haldane equation ( 1 ) is frequently used' to interpret experimental data of this type.
When an optimization is required in order to obtain the parameters k, K,, and Ki, it is advisable to rewrite eq. ( 1 ) in the following form': Among the three terms at the right-hand side of eq. ( 2), the first one may have very little weight with respect to the other two terms (or at least to one of them) for some Cs values or even for all the C , values that may have been used for the experiments. A typical case is the presence of strong substrate inhibition. Mathematically, the condition is KJCs + CsIKi*