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Use of the fluorescence probe 1-anilino-8-naphthalenesulfonate in predicting interindividual differences in the plasma protein binding of acidic drugs in rats

✍ Scribed by Jun Sato; Yuichi Sugiyama; Manabu Hanano


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
524 KB
Volume
73
Category
Article
ISSN
0022-3549

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## Abstract 8‐Anilino‐1‐naphthalenesulfonic acid (ANS) is a popular fluorescence probe, broadly used for the analysis of proteins, but the nature of its interaction with proteins and the high increase in the fluorescence intensity that takes place upon such process are still unclear. In the last fe