Use of the differential isotope method for studying the interaction between vapours of alkyl iodide and surface of red phosphorus

Investigation of the interaction of alky

Investigation of the interaction of alkyl iodide vapours with a carbon surface by kinetic and isotopic methods

✍ I. Kende; L. Guczi; D. Gál 📂 Article 📅 1959 🏛 Elsevier Science 🌐 English ⚖ 316 KB

Studies on the Interactions between Drug

Studies on the Interactions between Drugs and Estrogen: Analytical Method for Prediction System of Gynecomastia Induced by Drugs on the Inhibitory Metabolism of Estradiol Using Escherichia coli Coexpressing Human CYP3A4 with Human NADPH-Cytochrome P450 Reductase

✍ Takashi Satoh; Ken-ichi Fujita; Haruka Munakata; Shinji Itoh; Katsunori Nakamura 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 94 KB

To establish a prediction system for drug-induced gynecomastia in clinical fields, a model reaction system was developed to explain numerically this side effect. The principle is based on the assumption that 50% inhibition concentration (IC 50 ) of drugs on the in vitro metabolism of estradiol (E2)