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Use of the Comet-FISH Assay to Demonstrate Repair of the TP53 Gene Region in Two Human Bladder Carcinoma Cell Lines

โœ Scribed by McKenna, Declan J.; Rajab, Nor F.; McKeown, Stephanie R.; McKerr, George; McKelvey-Martin, Valerie J.


Book ID
111925028
Publisher
Bioone
Year
2003
Tongue
English
Weight
408 KB
Volume
159
Category
Article
ISSN
0033-7587

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## Background: Several convincing studies have shown that the hmsh2 gene plays major roles in mismatch repair by recognizing mismatched bases and preventing mutations during dna replication. loss of this function may result in the accumulation of dna replication errors or even the mutator phenotype