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Use of telemetry to record electrocardiogram and heart rate in freely moving mice

✍ Scribed by Klaas Kramer; Saskia A.B.E. van Acker; Hans-Peter Voss; Joop A. Grimbergen; Wim J.F. van der Vijgh; Aalt Bast


Book ID
113409791
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
683 KB
Volume
30
Category
Article
ISSN
1056-8719

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✍ Jahanavi Kharidia; Natalie D. Eddington πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 666 KB

Desethylamiodarone (DEA), the mjor active metabolite of amiodarone (AMD), plays a significant role in the electrophysiological effects observed during AMD thexapy. The pharmacokinetics and pharmacodynamics of DEA wcre studied in rats. Animals were administered DEA (20 or 40 mg kg-I) and blood sample