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Use of Sulfobutyl Ether β-Cyclodextrin as a Vehicle for d-threo-1-Phenyl-2-decanoylamino-3-morpholinopropanol-Related Glucosylceramide Synthase Inhibitors

✍ Scribed by Akira Abe; Susan Gregory; Lihsueh Lee; James A. Shayman


Book ID
102565820
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
62 KB
Volume
287
Category
Article
ISSN
0003-2697

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✦ Synopsis


D-threo-1-Phenyl-2-decanoylamino-3-morpholinopropanol (PDMP) 2 is a prototypic glucosylceramide synthase inhibitor first described by Vunnam and Radin (1). Subsequently, a series of PDMP homologues based