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Use of sodium in liquid ammonia for cleavage of N-proline peptides

✍ Scribed by Wilchek, M.; Sarid, S.; Patchornik, A.

Book ID
123554737
Publisher
Elsevier Science
Year
1965
Tongue
English
Weight
175 KB
Volume
104
Category
Article
ISSN
0304-4165

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✍ John Hempel; Hans JΓΆrnvall πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 English βš– 998 KB

Cleavage of X-Pro bonds with metallic sodium in liquid ammonia is a little-used method due to difficulties with handling of reagents, variable cleavage yields, and separation of peptides from salt byproducts. Construction of a small distillation/reaction apparatus permitted peptide incubations at th