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Use of selective noe measurements. A note of warning on the assignment of stereochemistry of 1-substituted 3-aryltetrahydroisoquinolines

✍ Scribed by D. Badía; E. Domínguez; C. Laborra

Publisher: Wiley (John Wiley & Sons)
Year: 2010
Weight: 112 KB
Volume: 97
Category: Article
ISSN: 0037-9646
DOI: 10.1002/bscb.19880970115

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✦ Synopsis

The stereochemistry of the 1-methyl-3-aryltetrahydroisoquinoline ( 2 ) was previously misassigned. Application of NOE difference spectroscopy has Fhown that its correct configuration is the ~na~h-l-methy1-3-(3,4-dirnethoxyphenyl)- S-bromo-7-methoxy-8-hydroxy-1,2,3,4-tetrahydroisoquinoline,

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