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Use of selective antagonists and antisense oligonucleotides to evaluate the mechanisms of BUBU antinociception

✍ Scribed by Daniel M Hutcheson; Pilar Sánchez-Blazquez; Marta Rodriguez-Diaz; Javier Garzon; Helmut Schmidhammer; Anna Borsodi; Bernard P Roques; Rafael Maldonado


Book ID
114017538
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
233 KB
Volume
383
Category
Article
ISSN
0014-2999

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## Abstract In the current study, we evaluated the efficiency of folate‐polyamidoamine dendrimers conjugates (FA‐PAMAM) for the __in situ__ delivery of therapeutic antisense oligonucleotides (ASODN) that could inhibit the growth of C6 glioma cells. Folic acid was coupled to the surface amino groups