Use of secondary chemical equilibria in liquid chromatography to determine dissociation constants of leukotriene B4 and prostaglandin B2

Simultaneous determination of thromboxan

Simultaneous determination of thromboxane B2, prostaglandin E2 and leukotriene B4 in whole blood by liquid chromatography/mass spectrometry

✍ Yoshiya Oda; Nariyasu Mano; Naoki Asakawa 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 674 KB

## Abstract Thromboxane B~2~, prostaglandin E~2~ and leukotriene B~4~ were simultaneously extracted from human whole blood without any time‐consuming evaporation or derivatization process, and directly determined by liquid chromatography/ionspray mass spectrometry. In order to obtain high sensitivi