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Use of Salmonella as a live drug delivery system

✍ Scribed by A. Flores; B. Mesa; E.M. Camacho; C. Medina; E. Santero


Publisher
Elsevier
Year
2009
Tongue
English
Weight
63 KB
Volume
25
Category
Article
ISSN
1871-6784

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Gelatin-methotrexate microspheres for intra-tumor administration have possibilities for minimizing systemic toxicities of methotrexate (MTX) and overcoming its resistance. Gelatin-MTX conjugates prepared by a carbodiimide reaction were crosslinked with glutaraldehyde to form microspheres (MTX:gelati