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Use of recombinant pemphigus vulgaris antigen in development of ELISA and IB assays to detect pemphigus vulgaris autoantibodies

✍ Scribed by Kailash Bhol; Shivraj Tyagi; K. Natarajan; Neville Nagarwalla; A. Razzaque Ahmed

Book ID
111093653
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
835 KB
Volume
10
Category
Article
ISSN
0926-9959

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Pemphigus vulgaris (PV) is an autoimmune blistering disease characterized by circulating pathogenic IgG antibodies against desmoglein 3 (Dsg3). The purpose of this study was to develop chimeric molecules for specific recognition and elimination of autoimmune B cells in PV. Mouse hybridoma cell lines