Use of porcine small intestinal submucosa in the surgical treatment of recurrent rectocele in a patient with Ehlers–Danlos syndrome type III

Temperature sensitivity of aberrant RNA

Temperature sensitivity of aberrant RNA splicing with a mutation in theG+5 position of intron 37 of the gene for type III procollagen from a patient with Ehlers–Danlos syndrome type IV

✍ Yuli Wu; Helena Kuivaniemi; Gerard Tromp; Deike Strobel; Anne M. Romanic; Darwin 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 828 KB

## Communicated by k e r n Peltonen A single-base mutation in intron 37 of the gene for type 111 procollagen (COL3A1) was found in a proband with the type IV variant of Ehlers-Danlos syndrome. Probeeprotection experiments with S 1 nuclease and RNA from fibroblasts incubated at 37°C demonstrated th