Use of plasminogen activators in venous thrombosis
β Scribed by Jack Hirsh; A. G. G. Turpie
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 677 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0364-2313
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## Background: Venous leg ulceration results from chronic venous insufficiency of the lower extremities. we recently showed that matrix metalloproteinase (mmp) -2 plays a major part in the pathogenesis of venous leg ulcers. in vitro activation of recombinant mmp-2 is controlled by the activity of t
## Laminated occlusive thrombus was induced in the rat inferior vena cava (IVC) by a distal stenosis and injection of thrombin. Immunocytochemistry was performed on serial cryostat sections of the thrombus for tissue plasminogen activator (tPA) and a variety of phenotype markers for mononuclear ce