Use of permanent hair dyes and bladder-cancer risk
β Scribed by Manuela Gago-Dominguez; J. Esteban Castelao; Jian-Min Yuan; Mimi C. Yu; Ronald K. Ross
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 65 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
A population-based case-control study was conducted in Los Angeles, California, which involved 1,514 incident cases of bladder cancer and an equal number of age-, sex-and ethnicity-matched controls. Information on personal use of hair dyes was obtained from 897 cases and their matched controls. After adjustment for cigarette smoking, a major risk factor for bladder cancer, women who used permanent hair dyes at least once a month experienced a 2.1-fold risk of bladder cancer relative to non-users (p for trend β«Ψβ¬ 0.04). Risk increased to 3.3 (95% CI β«Ψβ¬ 1.3-8.4) among regular (at least monthly) users of 15 or more years. Occupational exposure to hair dyes was associated with an increased risk of bladder cancer in this study. Subjects who worked for 10 or more years as hairdressers or barbers experienced a 5-fold (95% CI β«Ψβ¬ 1.3-19.2) increase in risk compared to individuals not exposed.
π SIMILAR VOLUMES
## Abstract Several cohort and caseβcontrol studies have found an increased risk of bladder cancer among hairdressers and barbers who are occupationally exposed to hair dyes. However, the carcinogenic risk associated with personal use of hair dyes remains uncertain since several large caseβcontrol
## Abstract Aromatic amine components in hair dyes and polymorphisms in genes that encode enzymes responsible for hair dye metabolism may be related to bladder cancer risk. We evaluated the association between hair dye use and bladder cancer risk and effect modification by __N__βacetyltransferaseβ1
## Abstract More than a decade ago, an increased risk for bladder cancer among male hairdressers was established. Frequent changes of hair dye formulations together with their widespread use call for safety guarantees. We carried out a followβup study of a cohort of 38,866 female and 6,824 male hai