Use of oral contraceptives and risk of invasive cervical cancer in previously screened women

✍ Scribed by K. Ebeling; P. Nischan; Ch. Schindler

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: French
• Weight: 462 KB
• Volume: 39
• Category: Article
• ISSN: 0020-7136
• DOI: 10.1002/ijc.2910390402

✦ Synopsis

Within the context of a larger hospital-based case-control ment of subjects lasted from September 1,1983 through March study carried out to assess the efficacy of cervical cancer 31. 1985. screening, the possible association between oral contracep-+he series comprises 129 with newly diagnosed tives and risk of invasive cervical cancer has been studied as well.

in the CDR cytological screening is an integral and histologically confirmed invasive cancer treated at the part of the gynaecoiogical basic care, only a few women re-Gynaecological University Hospital, Leipzig, or at the Gynaeported oral contraceptive use but had no Pap-smears in that COlOgical Hospital ofthe city of LeiPZig. study. Thus, the anaiysis was confined to those 129 cases and Controls (275) we= enrolled at the University Hospital for 275 controls who had at least one screening Papsmear in their Skin Diseases, Leipzig and, &cause of a deficiency in younger history and were below the age 55. The significantly increased also at the Orthopaedic university ~~~~ ~~i relative risks for users decreased after adjustment for factors since J&,uary 1, 1985. Of these controls, 248 had Hkin disof sexual behaviour and interval since last Pap-smear but remained statistically significant or at borderline significance eases, mainly inflammation Of the skin (128), and 27 had for some categories of usage. hi^ concerns, in particular, orthopaedic diseases. These hospitals draw their patients from long-term use (7 + years) and early onset of use (f 24 years) the Same area as that served by the gYnaeCOlOgiCal hospitals.

with relative risks of 1.8 and 3.0, respectively.