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Use of optimized 1D TOCSY NMR for improved quantitation and metabolomic analysis of biofluids

✍ Scribed by Peter Sandusky; Emmanuel Appiah-Amponsah; Daniel Raftery


Book ID
106401768
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
462 KB
Volume
49
Category
Article
ISSN
0925-2738

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## Abstract Two‐dimensional diffusion ordered spectroscopy (DOSY) ^1^H NMR is proposed to analyze drugs that are complex mixtures in order to discriminate genuine from fake formulations. The method was applied to the analysis of 17 formulations of sildenafil, one being genuine Viagra and the others