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Use of molecular variation in the NCBI dbSNP database

✍ Scribed by Stephen T. Sherry; Minghong Ward; Karl Sirotkin

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 249 KB
Volume: 15
Category: Article
ISSN: 1059-7794
DOI: 10.1002/(sici)1098-1004(200001)15:1<68::aid-humu14>3.0.co;2-6

No coin nor oath required. For personal study only.

✦ Synopsis

While high quality information regarding variation in genes is currently available in locus-specific or specialized mutation databases, the need remains for a general catalog of genome variation to address the large-scale sampling designs required by association studies, gene mapping, and evolutionary biology. In response to this need, the National Center for Biotechnology Information (NCBI) has established the dbSNP database http://ncbi.nlm.nih.gov/SNP/ to serve as a generalized, central variation database. Submissions to dbSNP will be integrated with other sources of information at NCBI such as GenBank, PubMed, LocusLink, and the Human Genome Project data, and the complete contents of dbSNP are available to the public via anonymous FTP.

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