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Use of mixed glycosidase for the removal of mucus from the rat nasal epithelium in SEM studies

✍ Scribed by Monteiro-Riviere, Nancy A. ;Jiang, Xue-Zhi


Publisher
Wiley (John Wiley & Sons)
Year
1986
Tongue
English
Weight
573 KB
Volume
3
Category
Article
ISSN
0741-0581

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✦ Synopsis


The surface layer of mucus, which obscures the epithelium from view, is a major obstacle when performing scanning electron microscopic studies of the nasal mucosa. Samples treated with a 1% mixed glycosidase solution for 1 or 2 minutes, followed by agitation, removed most of the mucus from the conchae without damaging the underlying epithelium. Removal of mucus allows the complete evaluation of the underlying epithelium in normal animals and the localization and characterization of lesions in animals exposed to nasal toxicants.