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Use of mini-octadecylsilane ultrasphere column in high-pressure liquid chromatography for protein structural studies

✍ Scribed by Ajit S. Bhown; J.Claude Bennett


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
402 KB
Volume
137
Category
Article
ISSN
0003-2697

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✦ Synopsis


Using a single mini-octadecylsilane (ODS) 5-Frn ultrasphere column (0.46 X 4.5 cm) and linear gradients of different solvents, all the aspects of protein structural analysis have been defined. The effectiveness of the system has been evaluated by separating the (Y and /j chains of hemoglobin and their tryptic peptides. then performing amino acid analysis and, finally, identifying the phenylthiohydantoin derivatives of amino acids,