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Use of metabolic activation systems of tulip bulbs in the ames test for environmental mutagens

✍ Scribed by Ken Higashi; Kie Ikeuchi; Yuji Karasaki

Book ID
112586487
Publisher
Springer
Year
1982
Tongue
English
Weight
281 KB
Volume
29
Category
Article
ISSN
0007-4861

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Mutagenicity of tetrachloroethene in the
Mutagenicity of tetrachloroethene in the ames testβ€”metabolic activation by conjugation with glutathione
✍ Vamvakas, Spyridon ;Herkenhoff, Martin ;Dekant, Wolfgang ;Henschler, Dietrich πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 649 KB

The mutagenicity of tetrachloroethene (tetra) and its S conjugate, S-(1,2,2-trichlorovinyl)glutathione (TCVG) was investigated using a modified Ames preincubation assay. TCVG was a potent mutagen in presence of rat kidney particulate fractions containing high concentrations of y-glutamyl transpeptid