Use of isotopes for studying reaction mechanisms
β Scribed by Uday Maitra; J. Chandrasekhar
- Publisher
- Indian Academy of Sciences
- Year
- 1997
- Tongue
- English
- Weight
- 503 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0971-8044
No coin nor oath required. For personal study only.
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## Abstract The use of kinetic isotope effects (KIEs) for the shortβlived radionuclides ^11^C and ^18^F in the study of reaction mechanisms is described using some examples. Leaving group fluorine KIEs (__k__^18^/__k__^19^) have been utilized to determine the rateβlimiting step for nucleophilic aro
## Abstract Perhaps the greatest influence that isotopic labelling experiments have had on organic mass spectrometry is that reaction mechanisms originally borrowed from the chemistry of neutral counterparts have proved to be inadequate for explaining the results. It was therefore necessary to devi