## Abstract Reversed‐phase liquid chromatography (RPLC) was combined with atmospheric pressure chemical ionization mass spectrometry (APCI‐MS), via a heated pneumatic nebulizer interface, for the determination of the polycyclic aromatic sulfur heterocycle (PASH) content of samples obtained by the f
✦ LIBER ✦
Use of immobilized copper ion chromatography and on-line mass spectrometry with atmospheric pressure chemical ionization for the profiling of complex mixtures of polycyclic aromatic compounds
✍ Scribed by Darren Thomas; Sheila M. Crain; P.Greig Sim; Frank M. Benoit
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 632 KB
- Volume
- 695
- Category
- Article
- ISSN
- 1873-3778
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Drug discovery is a fast growing field and the number of compounds generated daily by the pharmaceutical industry is enormous. The necessity of developing new experimental strategies and analytical methods to rapidly screen the pharmacokinetics (PK) behavior of these compounds becomes a real challen