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Use of High-Performance Liquid Chromatography To Study the Pharmacokinetics of Colistin Sulfate in Rats following Intravenous Administration

✍ Scribed by Li, J.; Milne, R. W.; Nation, R. L.; Turnidge, J. D.; Smeaton, T. C.; Coulthard, K.

Book ID
127000489
Publisher
American Society for Microbiology
Year
2003
Tongue
English
Weight
164 KB
Volume
47
Category
Article
ISSN
0066-4804

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A simple high-performance liquid chromatographic method was developed to study the pharmacokinetics of osthole in rat plasma. After addition of an internal standard (paeonol), plasma was deproteinized by acetonitrile for sample clean-up. The drugs were separated on a reversed-phase column and detect