𝔖 Bobbio Scriptorium
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Use of genetic mouse models in the study of diabetic nephropathy

✍ Scribed by Terri J. Allen; Mark E. Cooper; Hui Y. Lan

Book ID
107536105
Publisher
Current Science Inc.
Year
2004
Tongue
English
Weight
277 KB
Volume
4
Category
Article
ISSN
1534-4827

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## Abstract We have previously found progressive diabetic nephropathy in inducible cAMP early repressor (ICER IΞ³) transgenic (Tg) mice. The ICER IΞ³ Tg mouse is an interesting model of sustained hyperglycemia due to its low production of insulin and insulin‐producing Ξ² cells. Here in a longitudinal