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Use of fluoroform as a source of difluorocarbene in the synthesis of N-CF2H heterocycles and difluoromethoxypyridines

✍ Scribed by Thomoson, Charles S.; Wang, Linhua; Dolbier, William R.


Book ID
127236329
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
425 KB
Volume
168
Category
Article
ISSN
0022-1139

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## Abstract The pyrrolate ion **(5)** is shown to produce __N, N__′‐dipyrrolyl methane **(4)** when reacted with dichloromethane under conditions of weak counter‐ion association. 1‐Azoniafulvene ion **(13)** is suggested to be the key intermediate in this reaction. __N, N__′‐Dipyrrolyl methane **(4