It is unclear whether ovarian borderline tumors (tumors of low malignant potential) are independent entities or whether they are part of a continuum of tumor progression that culminates in ovarian carcinoma. Little is known about genetic abnormalities in borderline tumors because of the difficulty o
Use of fluorescence in situ hybridization and comparative genomic hybridization in the cytogenetic analysis of testicular germ cell tumors and uveal melanomas
β Scribed by Reinhard Becher; W.Michael Korn; Gabriele Prescher
- Book ID
- 114136148
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 730 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0165-4608
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To extend the results of conventional cytogenetic analysis of testicular germ cell tumors (TGCTs), we applied the new molecular cytogenetic method of comparative genomic hybridization (CGH), which enables the detection of chromosomal imbalances without the need for dividing cells. DNA from I I TGCTs