✦ LIBER ✦

Use of desmopressin to prevent bleeding complications in patients treated with aspirin

✍ Scribed by Dr. P. A. Flordal; S. Sahlin

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 253 KB
Volume: 80
Category: Article
ISSN: 0007-1323
DOI: 10.1002/bjs.1800800616

No coin nor oath required. For personal study only.

✦ Synopsis

Use of desmopressin t o prevent bleeding complications in patients treated with aspirin

Aspirin induces a haemorrhagic diathesis that persists f o r at least 1 week after discontinuation of the drug. The efect of the vasopressin analogue desmopressin was studied in 12 patients treated with aspirin who were undergoing cholecystectomy. Desmopressin was given to six of these patients. There were jive postoperative bleeding complications; all occurred in patients who had not received desmopressin (P < 0.05).

The bleeding time was prolonged in aspirin-treated patients and normalized by desmopressin ( P < 0.05

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