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Use of D-glucosamine and 2-deoxyglucose in the selective isolation of mutants of the yeast Lipomyces starkeyi derepressed for the production of extracellular endodextranase

✍ Scribed by A. Laires; I. Spencer-Martins; Prof. Dr. N. van Uden

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 223 KB
Volume: 23
Category: Article
ISSN: 0233-111X
DOI: 10.1002/jobm.19830230918

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✦ Synopsis

The glucose analogues 2-deoxyglucose and n-glucosamine repressed the production of extracellular endodextranase in the yeast Lipomyces starkeyi. Though both analogues were successfully used for the selective isolation of derepressed and hyperproductive mutants, 2-deoxyglucose proved to be superior to D-glUCOSamine with respect to effective concentration and the avoidance of background growth.

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