Use of cyclodextrins in isotachophoresis: VII. Resolution of structurally related and chiral phenothiazines
✍ Scribed by Ivan Jelínek; Jiří Dohnal; Jiří Snopek; Eva Smolková-Keulemansová
- Book ID
- 104144590
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 569 KB
- Volume
- 464
- Category
- Article
- ISSN
- 1873-3778
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✦ Synopsis
Commercially available phenothiazine derivatives were used for the study of cyclodextrin complex formation by cationic isotachophoresis with a-, /I-and y-cyclodextrin and methylated analogues of /3-cyclodextrin as leading electrolyte additives. The relationships between the type of solute substituent in the lo-and/or 2-position and the stability of the created cyclodextrin complex were studied and the results were utilized for the optimization of isotachophoretic conditions suitable for the resolution of the studied phenothiazine derivatives. Successful resolution of three racemic solutes was achieved.
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