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Use of competition dialysis in the discovery of G-quadruplex selective ligands

✍ Scribed by Patricia Ragazzon; Jonathan B. Chaires


Book ID
116986883
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
781 KB
Volume
43
Category
Article
ISSN
1046-2023

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## Abstract A new biomolecular device for investigating the interactions of ligands with constrained DNA quadruplex topologies, using surface plasmon resonance (SPR), is reported. Biomolecular systems containing an intermolecular‐like G‐quadruplex motif **1** (parallel G‐quadruplex conformation), a