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Use of charcoal hemoperfusion with sequential hemodialysis to reduce serum methotrexate levels in a patient with acute renal insufficiency

✍ Scribed by Roy Molina; Carol Fabian; Benjamin Cowley jr.


Book ID
115681440
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
230 KB
Volume
82
Category
Article
ISSN
1555-7162

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Use of plasma exchange in methotrexate r
✍ Karin Zattar Cecyn; Juno Lee; Tsutomo Oguro; Antônio Sérgio Petrilli; José Orlan 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 69 KB 👁 1 views

## Abstract Acute renal failure induced by methotrexate (MTX) can be lethal because renal excretion of the drug can be delayed. Pre‐existing renal impairment, abstention, or underdosage of folinic acid and inadequate hydration facilitate toxicity. The prolonged high serum levels of MTX result in se