Use of plasma exchange in methotrexate r
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Karin Zattar Cecyn; Juno Lee; Tsutomo Oguro; Antônio Sérgio Petrilli; José Orlan
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Article
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2003
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John Wiley and Sons
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English
⚖ 69 KB
👁 1 views
## Abstract Acute renal failure induced by methotrexate (MTX) can be lethal because renal excretion of the drug can be delayed. Pre‐existing renal impairment, abstention, or underdosage of folinic acid and inadequate hydration facilitate toxicity. The prolonged high serum levels of MTX result in se