A detailed investigation into the influence of phosphines, additives, bases and solvents on the Heck coupling reaction of 4-trifluoromethyl-1-chlorobenzene (2) is presented. It is shown that a number of catalyst systems exist for efficient cross coupling of electron-deficient aryl chlorides with var
✦ LIBER ✦
Use of bis(benzimidazolium)–palladium system as a convenient catalyst for Heck and Suzuki coupling reactions of aryl bromides and chlorides
✍ Scribed by Serpil Demir; Ismail Özdemir; Bekir Çetinkaya
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 130 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0268-2605
- DOI
- 10.1002/aoc.1039
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Scheme 1. Synthesis of magnetic nanoparticle-supported (b-oxoiminato)(phosphanyl) palladium complex 4. a) NH 2 (CH 2 ) 3 Si(OEt) 3 , microwave heating; b) EtOTl, [Pd 2 (m-Cl) 2 Me 2 (PPh 3 ) 2 ], tetrahydrofuran, RT; c) tetraethyl orthosilicate; d) 2, toluene, 100 8C, 12 h.