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Use of antifibrinolytics in orthotopic liver transplantation

✍ Scribed by R.P Kufner

Book ID
117229003
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
51 KB
Volume
32
Category
Article
ISSN
0041-1345

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Antifibrinolytics in orthotopic liver tr
Antifibrinolytics in orthotopic liver transplantation: Current status and controversies
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This article reviews the current status and controversies of the 3 commonly used antifibrinolytics-epsilon-aminocaproic acid, tranexamic acid and aprotinin-during liver transplantation. There is no general consensus on how, when or which antifibrinolytics should be used in liver transplantation. Alt

Antifibrinolytics do not reduce transfus
Antifibrinolytics do not reduce transfusion requirements in patients undergoing orthotopic liver transplantation
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Hemorrhaging continues to be a significant problem in patients undergoing orthotopic liver transplantation (OLT). Massive transfusion has been associated with morbidity and mortality. In addition, the use of large amounts of blood products for OLT can place a huge demand on the blood banking system