Use of an osteoinductive biomaterial as a bone morphogenetic protein carrier
โ Scribed by Huipin Yuan; J. D. de Bruijn; Xingdong Zhang; C. A. van Blitterswijk; K. de Groot
- Book ID
- 110325957
- Publisher
- Springer
- Year
- 2001
- Tongue
- English
- Weight
- 905 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0957-4530
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This study was carried out to determine the effect of recombinant human bone morphogenetic protein (rhBMP) pharmacokinetics (PK) on rhBMP-induced osteoinductive activity. It was our working hypothesis that the PK of a rhBMP significantly affects its osteoinductive activity. The PK of various rhBMPs
## Abstract The osteoinductivity of demineralized bone matrix (DBM) varies from donor to donor as a result of varying levels of multiple growth factors, matrix integrity, and artifacts from material processing. Many __in vitro__ assays are currently used for screening the osteoinductivity of DBM. T