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Use of amphotericin B aerosols for the prevention of pulmonary aspergillosis

โœ Scribed by J. Beyer; Claudia Weyer; W. Siegert; G. Barzen; Gisa Risse; S. Schwartz; K. Dullenkopf

Publisher
Springer-Verlag
Year
1994
Tongue
English
Weight
809 KB
Volume
22
Category
Article
ISSN
0300-8126

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โœ I. Ahmad; A. K. Sarkar; B. K. Bachhawat ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 395 KB

The efficacy and toxicity of free and liposome intercalated amphotericin-B (Amp-B) in controlling Aspergillosis, caused by Aspergillus fumigatus in BALB/c mice were studied. Liposomal Amp-B had higher LD50 (8.1 mg/kg) as compared to that of the free drug (1.2 mg/kg). An improvement in the therapeuti