The diagnosis of acute Epstein-Barr virus (EBV) infection is based frequently on the combination of positive viral capsid antigen (VCA) IgM antibodies and negative EB viral nuclear antigen 1 (EBNA-1) IgG antibodies. However, both VCA IgM and EBNA-1 IgG can provide false positive and false negative r
Use of a synthetic peptide-based elisa for the diagnosis of infectious mononucleosis and other diseases
β Scribed by John E. Geltosky; Richard S. Smith; Alice Whalley; Gary Rhodes
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 890 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0887-8013
No coin nor oath required. For personal study only.
β¦ Synopsis
A simple enzyme immunoassay has been developed based on measuring antibodies to synthetic peptides corresponding to sequences in the Epstein-Barr nuclear antigen (EBNA). This assay, which is repro-ducible, quantitative, and simple to perform and interpret, can be an effective tool to aid in the diagnosis of infectious mononucleosis and nasopharyngeal carcinoma.
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