✦ LIBER ✦

Use of a Pharmacophore Model for the Design of EGF-R Tyrosine Kinase Inhibitors: 4-(Phenylamino)pyrazolo[3,4- d ]pyrimidines

✍ Scribed by Traxler, Peter; Bold, Guido; Frei, Joerg; Lang, Marc; Lydon, Nicholas; Mett, Helmut; Buchdunger, Elisabeth; Meyer, Thomas; Mueller, Marcel; Furet, Pascal

Book ID: 118127754
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 387 KB
Volume: 40
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm970124v

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Use of a Pharmacophore Model for the Des

Use of a Pharmacophore Model for the Design of EGFR Tyrosine Kinase Inhibitors: Isoflavones and 3-Phenyl-4(1 H )-quinolones

✍ Traxler, Peter; Green, Jennifer; Mett, Helmut; Séquin, Urs; Furet, Pascal 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 180 KB

Tyrosine Kinase Inhibitors. 17. Irrevers

Tyrosine Kinase Inhibitors. 17. Irreversible Inhibitors of the Epidermal Growth Factor Receptor: 4-(Phenylamino)quinazoline- and 4-(Phenylamino)pyrido[3,2- d ]pyrimidine-6-acrylamides Bearing Additional Solubilizing Functions

✍ Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 286 KB

Tyrosine Kinase Inhibitors. 17. Irrevers

✍ Smaill, Jeff B.; Rewcastle, Gordon W.; Bridges, Alexander J.; Zhou, Hairong; Sho 📂 Article 📅 2000 🏛 American Chemical Society 🌐 English ⚖ 7 KB

Tyrosine Kinase Inhibitors. 12. Synthesi

Tyrosine Kinase Inhibitors. 12. Synthesis and Structure−Activity Relationships for 6-Substituted 4-(Phenylamino)pyrimido[5,4-d]pyrimidines Designed as Inhibitors of the Epidermal Growth Factor Receptor

✍ Rewcastle, Gordon W.; Bridges, Alexander J.; Fry, David W.; Rubin, J. Ronald; De 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 203 KB

ChemInform Abstract: Tyrosine Kinase Inh

ChemInform Abstract: Tyrosine Kinase Inhibitors. Part 7. 7-Amino-4-(phenylamino)- and 7- Amino-4-((phenylmethyl)amino)pyrido(4,3-d)pyrimidines: A New Class of Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor.

✍ A. M. THOMPSON; A. J. BRIDGES; D. W. FRY; A. J. KRAKER; W. A. DENNY 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB

Tyrosine Kinase Inhibitors. 13. Structur

Tyrosine Kinase Inhibitors. 13. Structure−Activity Relationships for Soluble 7-Substituted 4-[(3-Bromophenyl)amino]pyrido[4,3- d ]pyrimidines Designed as Inhibitors of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor

✍ Thompson, Andrew M.; Murray, Donna K.; Elliott, William L.; Fry, David W.; Nelso 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 262 KB