## Abstract Brush‐type chiral stationary phases (CSP) have been prepared both from a silica monolith and, separately, from 10 μm porous silica beads __via__ a process of __in‐column__ modification including attachment of the chiral selector __via__ copper‐catalyzed azide–alkyne cycloaddition. Azide
✦ LIBER ✦
Use of a new pirkle-type chiral stationary phase in analytical and preparative subcritical fluid chromatography of pharmaceutical compounds
✍ Scribed by Andrew M. Blum; Kenneth G. Lynam; Edgar C. Nicolas
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 700 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
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Enantiomeric separation of a variety of drugs and related compounds was achieved on an (S)-naphthylethylcarbamoylated-p-cyclodextrin (SNEC-CD) chiral stationary phase (CSP) using sub-and supercritical fluid chromatography (SFC). Compounds previously resolved on native or derivatized cyclodextrin CSP