𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Use of a molecular probe for detecting JCV DNA directly in human brain material

✍ Scribed by P. E. Gibson; S. D. Gardner; A. M. Field

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
572 KB
Volume
18
Category
Article
ISSN
0146-6615

No coin nor oath required. For personal study only.

✦ Synopsis

A hybridot assay using a radiolabelled JC virus probe has been used to detect the presence of JCV DNA in brain biopsy and postmortem brain samples from patients with neurological disease and possible progressive multifocal leucoencephalopathy. Sixty-nine brain samples from 45 patients were examined. Eleven samples from eight patients had detectable JCV DNA sequences. In seven of the eight patients this result was confirmed by electron microscopy and/or virus isolation or immunofluorescence.

πŸ“œ SIMILAR VOLUMES

Detection of Hepatitis B Virus DNA Direc
Detection of Hepatitis B Virus DNA Directly in Human Serum by a Simplified Molecular Hybridization Test: Comparison to HBeAg/ Anti-HBe Status in HBsAg Carriers
✍ Harvey M. Lieberman; Douglas R. Labrecque; Michael C. Kew; Stefanos J. Hadziyann πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 812 KB

A simple, direct molecular hybridization test was employed to detect hepatitis B virus (HBV) DNA sequences in human serum. In 61 HBsAg carriers, many with HBV-related diseases (chronic persistent hepatitis, chronic active hepatitis, or posthepatitic cirrhosis), 28/28 (100%) who were HBeAg+ and 16/32